Key result
PCI is linked to improved TAPSE-assessed RV function at 3 months in NSTEMI.
Why the study?
Right ventricular involvement in NSTEMI is poorly characterized despite its known impact on morbidity and mortality in STEMI.
Does successful percutaneous coronary intervention improve right ventricular function in patients presenting with a first NSTEMI?
Observational (n=150)
Does successful percutaneous coronary intervention improve right ventricular function in patients presenting with a first NSTEMI?
Right ventricular dysfunction is not uncommon in NSTEMI, and successful PCI is associated with significant improvement in RV function at 3 months.
RV recovery may occur after PCI in NSTEMI; hypothesis-generating and should not yet change practice.
BACKGROUND: Right ventricular involvement in ST segment elevation myocardial infarction (STEMI) entails an increased morbidity and mortality. However, very scarce data is present on its affection in the setting of non-ST segment elevation myocardial infarction (NSTEMI). AIM: To assess the affection of right ventricular function in patients presenting with NSTEMI undergoing an invasive procedure. SUBJECTS AND METHODS: One hundred and fifty patients admitted with a first NSTEMI and eligible for reperfusion therapy via invasive percutaneous coronary intervention. These patients were divided in two groups; group A including patients with normal RV function, and group B including patients with impaired RV function as diagnosed by tricuspid annular plane systolic excursion (TAPSE) cutoff value < 17 mm. All patients underwent angioplasty and were followed up in-hospital and for 3 months. RESULTS: , and TAPSE < 17 mm. CONCLUSION: RV dysfunction is not uncommon in NSTEMI when using the definition of TAPSE < 17 mm. Following up RV function by TAPSE, showed significant improvement after 3 months with successful PCI as compared to baseline. We recommend assessing and following up RV function in all patients admitted with a NSTEMI.
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Shawky et al. (2018) conducted an observational in Non-ST-segment elevation myocardial infarction (NSTEMI) (n=150). Impaired right ventricular function (TAPSE < 17 mm) vs. Normal right ventricular function was evaluated on Right ventricular function improvement at 3 months. Right ventricular function assessed by TAPSE showed significant improvement 3 months after successful percutaneous coronary intervention compared to baseline in patients with NSTEMI.
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