Key result
A novel RP-HPLC method was successfully developed and validated for the simultaneous estimation of carvedilol and ivabradine, demonstrating high precision, accuracy, and stability.
The study provides a validated RP-HPLC analytical method for the simultaneous determination of carvedilol and ivabradine in pharmaceutical formulations.
May aid research assays and formulation analysis; leaves open clinical adoption without further validation.
A simple, sensitive, precise, specific, rapid, accurate, and novel reverse phase high performance liquid chromatography (RP- HPLC) method for determining carvedilol (CAR) and ivabradine (IVA) in bulk and its formulation has been developed validated.
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Mohammed et al. (2022) studied this question. RP-HPLC method for Carvedilol and Ivabradine was evaluated on Method validation parameters (linearity, accuracy, precision, LOD, LOQ). A novel RP-HPLC method was successfully developed and validated for the simultaneous estimation of carvedilol and ivabradine, demonstrating high precision, accuracy, and stability.
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