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Treatment of young and mature mice with potent preparations of mouse interferon results in a marked enhancement of the expression of histocompatibility antigens on the surface of thymocytes and splenic lymphocytes, as measured by an enhanced absorption of alloantiserum. These modifications in the expression of cell surface antigens may reflect an effect of interferon on lymphocyte naturation and may be relevant to theffect of interferon on lymphocyte function.
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Lindahl et al. (1976) studied this question.
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