Acute heart failure caused by mechanical valve thrombosis in patient with dialysis following aortic and mitral valve replacement： A case report

Q: What is the clinical evidence from this study?

Study design: Case Report. Population: Acute heart failure caused by mechanical valve thrombosis (n=1). Intervention: Mitral valve replacement. Primary outcome: Improvement of heart failure.

Tomohisa Tabuchi; Tsubasa Uruta; 将之 大塚; Takuma KOJOU; Yozo Yoshimine; 東福勝徳; Erika Yamashita; Kazuyuki Tanoue; Hideyuki Fumoto; Haruhito Yoshimine; Yoshihiro Nakayama; Daisuke Ikeda; Toru Ikeda; Shuji Kanmura

doi:10.4009/jsdt.59.522

January 1, 2026Nihon Toseki Igakkai ZasshiOpen Access

Acute heart failure caused by mechanical valve thrombosis in patient with dialysis following aortic and mitral valve replacement： A case report

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Key result

Prompt mitral valve replacement resolves acute HF from mechanical valve thrombosis in a hemodialysis patient.

n=1

Key Points

To describe a case of acute heart failure caused by mechanical mitral valve thrombosis during maintenance hemodialysis following dual aortic and mitral valve replacement.
Assessed a 63-year-old woman on maintenance hemodialysis presenting with dyspnea 5 years after mechanical aortic and mitral valve replacement and coronary artery bypass grafting.
Conducted serial transthoracic echocardiography, chest computed tomography, fluoroscopy, and emergency repeat valve surgery.
Echocardiography showed rapid progression of prosthetic mitral stenosis from hospital day 2 (mean pressure gradient 20 mmHg, valve area 1.40 cm2) to day 4 (mean pressure gradient 24 mmHg, valve area 0.75 cm2).
Emergency redo mitral valve replacement on hospital day 5 revealed a 5 mm white thrombus lodged at the mechanical valve hinge, and extraction of the valve successfully resolved the heart failure.

Study Design

Type

Case Report (n=1)

Multicenter

No

PICO

P

Population

A 60-year-old woman on hemodialysis who developed acute heart failure due to mechanical valve thrombosis 5 years after aortic and mitral valve replacement.

I

Intervention / Comparator

Mitral valve replacement

O

Primary Outcome

Improvement of heart failure

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Implication

Case report reveals mechanical valve thrombosis causing acute heart failure in a hemodialysis patient, highlighting the challenge of strict anticoagulation management.

Abstract

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Cite This Study

Tabuchi et al. (2026) conducted a case report in Acute heart failure caused by mechanical valve thrombosis (n=1). Mitral valve replacement was evaluated on Improvement of heart failure. Prompt mitral valve replacement successfully treated acute heart failure caused by mechanical valve thrombosis in a hemodialysis patient with difficult anticoagulant management.

synapsesocial.com/papers/6abb0703077501092874c06d https://doi.org/10.4009/jsdt.59.522

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Acute heart failure caused by mechanical valve thrombosis in patient with dialysis following aortic and mitral valve replacement： A case report

Key Points

Study Design

PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Acute heart failure caused by mechanical valve thrombosis in patient with dialysis following aortic and mitral valve replacement： A case report

Key Points

Study Design

PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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