Key result
Aortic dimensions scale tightly with the square root of BSA in young individuals.
Why the study?
Establishing normal aortic dimensions in healthy children and young adults is important to identify aortic valve and ascending aorta pathology, especially aortic root dilatation.
Cross-Sectional (n=702)
No
Effect estimate: R-squared 0.89 for aortic valve annulus, 0.86 for sinuses of Valsalva and sinotubular junction
Echocardiographic measurements of the aortic root in healthy children and young adults correlate strongly with the square root of body surface area, providing reference values for clinical use.
BACKGROUND: To be able to determine aortic valve and ascending aorta pathology, especially aortic root dilatation, it is important to establish normal aortic dimensions. The aim of the study was to measure the dimensions of the aorta in normal healthy children and young adults in Slovakia. PATIENTS AND METHODS: 702 healthy subjects, from newborns to 20 years of age, were examined at our institution. The study was carried out prospectively, by a single observer, using digitized two-dimensional (2D), Doppler and M-mode echocardiography. The aorta was measured at 3 sites: 1. aortic valve annulus, 2. sinuses of Valsalva, 3. sinotubular junction. Patients were divided into 28 groups according to their body surface area (BSA)--from 0.15 to 2.0 m2. All data were statistically evaluated (mean value, 5th and 95th percentile for all BSA groups) and regression equations were calculated for each parameter. RESULTS: All 3 measured aortic parameters correlated closely. Measures of correlation (R-squared) for aortic parameters with the square root of BSA were high: 0.89 for aortic valve annulus, 0.86 for sinuses of Valsalva and 0.86 for sinotubular junction (Tab. 3, Fig. 7, Ref 13). Full Text (Free, PDF) www.bmj.sk
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Kaldarárová et al. (2007) conducted a cross-sectional in Healthy (n=702). Body surface area was evaluated on Correlation of aortic parameters with the square root of body surface area (R-squared 0.89 for aortic valve annulus, 0.86 for sinuses of Valsalva and sinotubular junction). Aortic dimensions in healthy children and young adults correlated closely with the square root of body surface area (R-squared 0.89 for aortic valve annulus, 0.86 for sinuses of Valsalva).
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