Key result
Exercise LVEF response links to long-term cardiac death and surgical intervention risk.
Why the study?
The prognostic value of exercise radionuclide cineangiography early after coronary artery bypass grafting in elderly patients was not well established.
Does exercise radionuclide cineangiography predict long-term prognosis in elderly patients post coronary artery bypass grafting?
Cohort (n=87)
Does exercise radionuclide cineangiography predict long-term prognosis in elderly patients post coronary artery bypass grafting?
Exercise radionuclide cineangiography performed 4-8 months post-CABG provides prognostic value for long-term mortality and cardiac events in elderly patients.
Answers are grounded in this paper and cite their sources.
Exercise LVEF change may stratify risk in elderly post-CABG; extends prior data but leaves open prospective validation before routine use.
ISSUE: The immediate benefits of coronary artery bypass grafting may only be transient. Recent studies which showed that exercise radionuclide cineangiography studies may predict cardiac events and survival had evaluated post coronary artery bypass grafting patients of all ages. This prospective study was done on an elderly subgroup. METHODS: The results of exercise radionuclide cineangiography performed early (4-8 months) post coronary artery bypass grafting were correlated over six years of follow up with mortality, major surgical and nonsurgical cardiac events, and cardiac event free survival in 87 consecutive patients at or above 65 years. RESULTS: The rest to peak exercise difference in left ventricular ejection fraction correlated with later cardiac death and the need for surgical interventions, while rest left ventricular ejection fraction correlated only with the latter parameter. CONCLUSIONS: Assessment of left ventricular ejection fraction at rest and at exercise has prognostic values after coronary artery bypass grafting in elderly patients. Exercise radionuclide cineangiography carried out soon after coronary artery bypass grafting might be considered an useful tool to assess patient prognosis. The efficacy of exercise radionuclide cineangiography carried out soon after coronary artery bypass grafting should be confirmed in larger and more varied patient subgroups.
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Shapira et al. (2000) conducted a cohort in Post coronary artery bypass grafting (n=87). Exercise radionuclide cineangiography was evaluated on Mortality, major surgical and nonsurgical cardiac events, and cardiac event free survival. The rest to peak exercise difference in left ventricular ejection fraction assessed by radionuclide cineangiography correlated with later cardiac death and the need for surgical interventions.
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