A cardiac paraganglioma

Q: What is the clinical evidence from this study?

Study design: Case Report. Population: Cardiac paraganglioma (n=1). Intervention: Surgical resection. Primary outcome: Normalization of blood pressure and glucose.

Q: What does this research mean for the field?

Cardiac paraganglioma can present in young adults with classic adrenergic symptoms including severe headaches, palpitations, and excessive sweating. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

R. A. Plaatjies; Juliet Venter

doi:10.24170/8-1-1926

April 6, 2017SA HeartOpen Access

A cardiac paraganglioma

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Key Points

To report the clinical features, diagnostic evaluation, and surgical intervention for a rare functional cardiac paraganglioma presenting with severe hypertension and metabolic derangements.
Evaluated a 31-year-old man presenting with headache, palpitations, sweating, blood pressure of 180/116mmHg, and random glucose of 16.4mmol/l using echocardiography, 64-slice chest CT, and 24-hour urine fractionated metanephrines.
Stabilized the patient with insulin and multi-agent antihypertensive therapy prior to surgical resection of the pericardial mass after two weeks.
Imaging revealed a 3.7cm mass in the right atrio-ventricular groove, while biochemical tests demonstrated marked elevation of 24-hour urine nor-metanephrine at 17 677nmol/24hhrs and chromogranin A at 89u/l.
Surgical excision confirmed a paraganglioma supplied by a branch of the conus artery, leading to complete normalization of blood pressure and glucose levels without the need for post-operative medications.

Study Design

Type

Case Report (n=1)

Structured PICO

P

Population

A 31-year-old man presenting with severe headache, palpitations, excessive sweating, and severe hypertension who was diagnosed with a cardiac paraganglioma.

I

Intervention

Surgical resection of the cardiac paraganglioma.

O

Outcome

Normalization of blood pressure and glucose levels.surrogate

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Implication

Surgical resection of a rare cardiac paraganglioma successfully resolved secondary severe hypertension and diabetes in a young patient.

Abstract

A 31-year-old man presented with a month’s history of severe headache, palpitations and excessive sweating. He had no prior illnesses and was not taking any medication. He was a non-smoker and a teetotaller. His parents had both died but he did not know the cause of their deaths.

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Cite This Study

Plaatjies et al. (2017) conducted a case report in Cardiac paraganglioma (n=1). Surgical resection was evaluated on Normalization of blood pressure and glucose.

synapsesocial.com/papers/6ac19d70aeea5716e8c6c645 https://doi.org/10.24170/8-1-1926

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A cardiac paraganglioma

Key Points

Study Design

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

A cardiac paraganglioma

Key Points

Study Design

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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