Key result
Coronary stenting improves event-free survival by ~10% absolute over balloon angioplasty in narrow arteries.
Why the study?
The effectiveness of balloon angioplasty compared with coronary stenting in narrow coronary arteries was assessed due to uncertainty in optimal treatment.
Does coronary stenting improve event-free survival compared to balloon angioplasty in patients with narrow coronary arteries?
RCT (n=100)
randomly allocated
No
Does coronary stenting improve event-free survival compared to balloon angioplasty in patients with narrow coronary arteries?
Coronary stenting provides superior event-free survival and lower restenosis rates compared to balloon angioplasty for narrow coronary arteries.
Answers are grounded in this paper and cite their sources.
Supports stenting over balloon angioplasty for narrow lesions; confirms randomized superiority in event-free survival.
Objective: The study aimed to assess the effectiveness of balloon angioplasty compared with coronary stenting in narrow coronary arteries. Study Design: A comparative study Place and Duration of Study: This study was conducted at the department of cardiology, Lady Reading Hospital Peshawar. The study duration was one year from June 2022 to June 2023. Methods: This comparative study was carried out at the department of cardiology, Lady Reading Hospital Peshawar. The study duration was one year from June 2022 to June 2023. A total of 100 patients with lesions in narrow coronary arteries were enrolled. Participants were randomly allocated to get stent placement or traditional balloon angioplasty. Each participant signed a written statement of informed permission. During a year, the rates of clinical events were assessed. SPSS version 25 was used for descriptive statistics. Results: Total 100 patients were enrolled in this study. Male patients were 59(59%) and female patients were 41 (41%). Each group consists of 50 patients with comparable baseline demographics and angiography findings. Major adverse cardiac events and the rate of success of angiography were equivalent, according to treatment analysis: 5.4% and 95.6% in the case of coronary stenting and 5.6% and 93.5% in the case of balloon angioplasty. 3.8% of patients had significant closure changes throughout the course of 30 days. At six months, stenting substantially increased the lumen by1.52 mm and balloon angioplasty by 1.32 mm. (p=0.002) and the post-procedural lumen diameter was increased 2.31mm by stent and 1.82 mm by balloon angioplasty (p=0.002). The restenosis incidence after coronary stenting and balloon angioplasty was found to be 35% and 55%, respectively. The survival rates (event-free) after coronary stenting and angioplasty were respectively 75% and 65% (p=0.034). Conclusion: Our study concludes that lesions in narrow coronary arteries may respond well to optimum balloon angioplasty with subsequent stenting. The restenosis rates were reported to be 35% and 55% in coronary stenting and balloon angioplasty respectively.
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Tariq Nawaz , Muhammad Amin , Suliman Khan , Syed Muhammad Nayab Ali (2023) conducted an RCT in lesions in narrow coronary arteries (n=100). Coronary stenting vs. Traditional balloon angioplasty was evaluated on Event-free survival (p=0.034). Coronary stenting significantly improved event-free survival to 75% compared to 65% with balloon angioplasty in patients with narrow coronary arteries.
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