Key result
Preoperative HbA1c fails to predict postoperative AF in diabetic patients undergoing on-pump CABG.
Why the study?
The relationship between preoperative HbA1c levels and the development of postoperative atrial fibrillation in diabetic patients undergoing on-pump coronary artery bypass graft was unclear.
Observational (n=288)
p-value: p=0.170
HbA1c levels were not independently linked to PoAF; leaves open whether glycemic optimization modifies arrhythmia risk in diabetic CABG patients.
BACKGROUND: We aimed to determine the relationship between hemoglobin A1c (HbA1c) levels and the development of postoperative atrial fibrillation (PoAF). METHODS: Two hundred and eighty-eight patients diagnosed with diabetes mellitus and undergoing on-pump coronary bypass were included in the study. Those with serum HbA1c levels between 5.5% and 7.0% were defined as Group 1, those with serum HbA1c levels between 7.1% and 8.9% were defined as Group 2, while those with serum HbA1c levels 9.0% and above formed Group 3. Data between groups were compared. The predictive values of the independent variables for the development of PoAF were measured. RESULTS: We did not find a difference between groups in terms of development PoAF (p = .170). The presence of hypertension was determined as an independent predictor for the development of PoAF (p = .003), but not HbA1c levels (p = .134). There was 50.5% sensitivity and 61.1% specificity for HbA1c values of 9.06% and above to predict PoAF (area under curve: 0.571, p = .049). CONCLUSIONS: HbA1c levels were not an independent predictor of PoAF development. However, we think that high HbA1c levels may be a risk factor for the development of PoAF.
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Yavuz et al. (2022) conducted an observational in Diabetes mellitus undergoing on-pump coronary artery bypass graft (n=288). Preoperative HbA1c levels vs. Lower HbA1c levels was evaluated on Development of postoperative atrial fibrillation (PoAF) (p=0.170). Preoperative HbA1c levels were not an independent predictor for the development of postoperative atrial fibrillation in diabetic patients undergoing on-pump CABG (p=0.134).
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