Key result
Preoperative HbA1c ≥7% was associated with a higher incidence of new-onset atrial fibrillation compared to HbA1c <7% in diabetic patients after on-pump CABG.
Why the study?
Elevated preoperative HbA1c levels have been suggested as a potential risk factor for post-CABG atrial fibrillation in diabetic patients, but the association remains unclear.
Does elevated preoperative HbA1c (≥7%) increase the incidence of new-onset atrial fibrillation in diabetic patients undergoing on-pump CABG?
Cross-Sectional (n=60)
No
Does elevated preoperative HbA1c (≥7%) increase the incidence of new-onset atrial fibrillation in diabetic patients undergoing on-pump CABG?
Elevated preoperative HbA1c (≥7%) is significantly associated with a higher incidence of new-onset atrial fibrillation and fewer complication-free recoveries in diabetic patients undergoing on-pump CABG.
Answers are grounded in this paper and cite their sources.
May warrant closer AF monitoring in diabetic CABG patients with HbA1c ≥7%; leaves open whether optimizing glycemia reduces incidence.
Introduction: Atrial fibrillation (AF) is a common complication following coronary artery bypass grafting (CABG) surgery, particularly in diabetic patients. Elevated preoperative HbA1c levels have been suggested as a potential risk factor for postoperative AF; however, the association remains unclear. This study aimed to investigate the association between preoperative HbA1c levels and the incidence of new-onset atrial fibrillation during the early postoperative period in diabetic patients undergoing on-pump CABG surgery in Bangladesh. Methods: This observational cross-sectional study was conducted at the Department of Cardiac Surgery, National Institute of Cardiovascular Disease, Dhaka, Bangladesh. A total of 60 diabetic patients undergoing on-pump CABG were included and divided into two groups: Group-1 (HbA1c <7%, n=30) and Group-2 (HbA1c ≥7%, n=30). Data were collected using a preformed data collection sheet, and statistical analysis was performed using the chi-square test, Fisher's test, and student's t-test. Result: In this study, Group-1 (HbA1c <7%) consisted of 30 patients, while Group-2 (HbA1c ≥7%) also comprised 30 patients. The mean age of Group-1 was 58.50±6.80 years, and that of Group-2 was 50.53±6.01 years (p < 0.001). The distribution of preoperative variables such as single, double, and triple vessel disease, hypertension, history of antiarrhythmic drug use, and NYHA class III and IV showed no significant differences between the groups (p > 0.05). However, preoperative HbA1c levels were significantly different between the two groups (6.11±0.44 in Group-1 vs. 7.98±0.55 in Group-2, p < 0.001). The incidence of new-onset atrial fibrillation during the early postoperative period was significantly higher in Group-2 (63.33%) than in Group-1 (30.00%, p < 0.05). A significant association was also observed between postoperative atrial fibrillation and hypertension (p < 0.05). Patients in Group-2 experienced a higher rate of postoperative complications, .......
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Ahsan et al. (2023) conducted a cross-sectional in Diabetic patients undergoing on-pump CABG (n=60). Preoperative HbA1c ≥7% vs. Preoperative HbA1c <7% was evaluated on Incidence of new-onset atrial fibrillation (p=<0.05). Preoperative HbA1c ≥7% was associated with a higher incidence of new-onset atrial fibrillation compared to HbA1c <7% in diabetic patients after on-pump CABG.
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