Key result
Eruptive xanthomas signal severe metabolic syndrome components like hypertriglyceridemia and diabetes.
Why the study?
Eruptive xanthomas are a rare but important clinical finding associated with metabolic syndrome conditions such as diabetes mellitus and hypertriglyceridemia.
Case Report (n=1)
Eruptive xanthomas can serve as an important clinical indicator of severe hypertriglyceridemia and metabolic syndrome.
Eruptive xanthomas may prompt lipid evaluation in metabolic syndrome; this case leaves open the need for larger confirmatory studies.
Eruptive xanthomas are characterized by large numbers of yellow papules, typically 1-4 m in size, sometimes with an erythematous halo, sometimes pruritic, of sudden onset and generally observed on the extensor surfaces of the extremities. These are seen in less than 0.1% of diabetic patients. Diabetes mellitus is the most common secondary cause of type 5 hyperlipoproteinemia, a form of chylomcronemia. Eruptive xanthomas generally emerge at triglyceride levels above 2000 mg/dL proceeding with chylomicronemia. This case report of a 36-year-old woman diagnosed with eruptive xanthoma on the basis of clinical and histopathological findings is presented in order to emphasize that these are an important finding of diseases associated with metabolic syndrome, such as diabetes mellitus and hypertriglyceridemia.
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E. et al. (2016) conducted a case report in Eruptive xanthomas and metabolic syndrome (n=1). Metabolic syndrome and hypertriglyceridemia was evaluated on Clinical and histopathological findings of eruptive xanthoma. A 36-year-old woman presented with eruptive xanthomas, highlighting them as an important clinical finding in diseases associated with metabolic syndrome such as diabetes and hypertriglyceridemia.
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