Key result
Guideline-directed medical therapy prescribed in only ~18% of HFrEF patients, linked to lower readmissions.
Why the study?
Chronic heart failure in Thailand is associated with high mortality and medical costs, necessitating evaluation of treatment adherence to guidelines.
Does guideline-recommended medical therapy reduce re-admission rates in patients with chronic heart failure and LVEF < 40%?
Observational (n=51)
No
Does guideline-recommended medical therapy reduce re-admission rates in patients with chronic heart failure and LVEF < 40%?
Adherence to guideline-directed medical therapy for HFrEF remains suboptimal in this Thai cohort, but patients receiving recommended treatments had lower re-admission rates.
Guideline-directed therapy remains underused in Thai chronic HFrEF; leaves open whether increasing prescriptions reduces readmissions in real-world settings.
Chronic heart failure has become one of the major health problems in Thailand, due to high mortality rate and excessive medical expenditure. Thus, treatment which is based on guideline recommendations is important. The present study was a retrospective observational study aimed to evaluate medication treatment in chronic heart failure patients with left ventricular ejection fraction less than 40% compared with the guideline recommendations at Hua-Hin Hospital. The data was analyzed by descriptive statistics and chi-square test. Fifty- one chronic heart failure patients with left ventricular ejection fraction less than 40% were included in the study. The results showed that the three most-prescribed medications were loop diuretics (92.2%), beta blockers (56.8%) and ACEIs or ARBs (52.9%), respectively. Moreover, 29.4% of patients used a combination of ACEIs or ARBs and beta blockers. As well, 17.6% of patients were treated with ACEIs or ARBs combined with beta blockers and mineralocorticoid antagonist, which was consistent with guidelines for recommended treatments. In addition, a re-admission rate was lower in the group taking guideline-recommended treatments.
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Boonmuang et al. (2018) conducted an observational in Chronic heart failure (n=51). Guideline-recommended treatments vs. Non-guideline-recommended treatments was evaluated on Medication prescription rates and re-admission rate. Guideline-recommended treatments were prescribed to 17.6% of chronic heart failure patients with LVEF <40% and were associated with a lower re-admission rate.
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