A Review on Qsar Studies

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QSAR has been applied extensively and successfully over several decades to find predictive models for activity of bioactive agents.QSAR have brought revolution in drug discovery process by development of the mathematical relationships linking chemical structures and pharmacological activity in quantitative matter of series of compound.The mathematical relationship between molecular descriptors and activity are used to find the parameters affecting the biological activity and estimate the property of other molecules.Description of the molecular structure, electronic orbital reactivity and the role of structural and steric components have been the subject of mathematical and statistical analysis.