Key result
Simplified prediction model correctly risk-stratifies ~95% of ED dyspnea patients for PE.
Why the study?
A simple clinical model for predicting pulmonary embolism in patients with acute dyspnea in the emergency room was needed.
Population
56 patients with PE and 92 without PE presenting with acute dyspnea in the emergency room
Comparison
Patients with PE vs patients without PE
Design
Observational study
Authors
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May aid pretest PE probability estimation in acute dyspnea; leaves open prospective validation before clinical adoption.
Observational (n=188)
No
Chen et al. (2006) conducted an observational in Acute dyspnea and suspected pulmonary embolism (n=188). Simplified clinical prediction model was evaluated on Positive predictive value (PPV) for high probability and negative predictive value (NPV) for low probability of pulmonary embolism. A simplified clinical prediction model accurately categorized 95% of emergency room patients with acute dyspnea into high or low probability of pulmonary embolism, yielding a positive predictive value of 94.1% and a negative predictive value of 94.4%.
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