Key result
Type 2 diabetes family history is not linked to altered diurnal blood pressure profiles in offspring.
Why the study?
It was unclear whether elevated blood pressure and impaired nocturnal BP reduction are present in nondiabetic first-degree relatives of type 2 diabetic patients.
Population
253 offspring of type 2 diabetic patients and 275 offspring of nondiabetic subjects
Comparison
Nondiabetic glucose-tolerant offspring of type 2 diabetic subjects vs offspring of nondiabetic subjects
Design
Cross-sectional study
Authors
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No early BP abnormalities in nondiabetic offspring of T2D patients; leaves open later-onset risk or non-BP pathways.
Cross-Sectional (n=528)
p-value: p=>0.05
Foss et al. (2000) conducted a cross-sectional in Family history of type 2 diabetes (n=528). Offspring of type 2 diabetic patients vs. Offspring of nondiabetic subjects was evaluated on Blood pressure level and diurnal blood pressure profile (p=>0.05). Nondiabetic offspring of type 2 diabetic patients had a preserved diurnal blood pressure profile and normal blood pressure levels (P>0.05) compared with offspring of nondiabetic subjects.
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