The Role of Proton Pump Inhibitors in Acute Stress Ulcer Prophylaxis in Mechanically Ventilated Patients

In Brief This article reviews the use of proton pump inhibitors, other pharmacological therapies, and nonpharmacological therapies for the prevention of acute stress ulcers in critically ill patients. This article discusses the use of proton pump inhibitors to prevent stress ulcers in many intensive care unit patients. The pathophysiology of stress ulcers is discussed as well as a case study.