Key result
Definite ECG findings in hospitalized AMI drop ~50% over an 8-year period.
Why the study?
It was uncertain whether acute myocardial infarctions are becoming smaller over time in the general population.
Population
11,487 definite or possible AMIs aged 25-64 years in three areas of Finland
Comparison
Trends in ECG and enzyme findings over time from 1983 to 1990
Design
Community-based observational register study according to WHO MONICA protocol
Follow-up
8 years
Authors
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Supports trend to smaller hospitalized AMIs; extends prior registry observations but leaves mechanisms and practice implications open.
Observational (n=8,439)
Yes
p-value: p=<0.0001
Salomaa et al. (1995) conducted an observational in Acute myocardial infarction (n=8,439). Calendar year (1983-1990) was evaluated on Trends in ECG findings classified as definite or probable, and trends in enzyme findings classified as abnormal or equivocal (p=<0.0001). Over an 8-year period, the proportion of definite ECG findings among hospitalized AMI patients declined by almost half, and abnormal enzyme findings declined by almost one-third.
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