Key result
Thrombolysis successfully rescues cardiac arrest from massive PE under general anesthesia.
Why the study?
Massive pulmonary embolism occurring perioperatively under general anesthesia is rare, difficult to diagnose quickly, and life-threatening, requiring early diagnosis and timely treatment.
Case Report (n=1)
No
Thrombolysis may be feasible in anesthesia-related massive PE arrest; leaves open need for prospective data on safety and outcomes.
Background: While pulmonary embolism (PE) is a common occurrence, a large life-threatening PE is not. Herein, we discuss the case of a patient with a life-threatening PE that occurred under general anesthesia. Case presentation: We present the case of a 59-year-old male patient who was at bed rest for several days due to trauma, which resulted in femoral and rib fractures and a lung contusion. The patient was scheduled for femoral fracture reduction and internal fixation under general anesthesia. After disinfection and surgical towel laying, there was a sudden occurrence of severe PE and cardiac arrest; the patient was successfully resuscitated. Computed tomography pulmonary angiography (CTPA) was performed to confirm the diagnosis, and the patient's condition improved after thrombolytic therapy. Unfortunately, the patient's family eventually discontinued treatment. Discussion: Massive PE frequently occurs suddenly, may endanger a patient's life at any point in time, and cannot be diagnosed quickly on the basis of clinical manifestations. Although the vital signs fluctuate greatly and there is insufficient time to conduct more tests, some factors such as special disease history, electrocardiography, end-tidal carbon dioxide, and blood gas analysis may help us determine the preliminary diagnosis; however, the final diagnosis is made using CTPA. Current treatment options include thrombectomy, thrombolysis, and early anticoagulation, of which thrombolysis and early anticoagulation are the most feasible. Conclusion: Massive PE is a life-threatening disease that requires early diagnosis and timely treatment to save patients' lives.
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Li et al. (2023) conducted a case report in Massive pulmonary embolism and cardiac arrest (n=1). Cardiopulmonary resuscitation and thrombolysis was evaluated on Successful resuscitation and stabilization. A 59-year-old male patient who suffered cardiac arrest due to massive pulmonary embolism under general anesthesia was successfully resuscitated and treated with thrombolysis.
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