Key result
Coronary balloon inflation triggers reversible regional LV dysfunction, causing akinesia or dyskinesia in ~71% of patients.
Why the study?
Balloon inflation during coronary angioplasty causes transient coronary occlusion, providing a model to evaluate regional myocardial responses to transient ischemia.
Observational (n=20)
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PTCA balloon occlusion models reversible ischemic LV dysfunction in normal hearts; leaves open applicability and safety in patients with baseline dysfunction.
Wohlgelernter et al. (1986) conducted an observational in Isolated stenosis of the proximal left anterior descending coronary artery (n=20). Balloon inflation during coronary angioplasty vs. Baseline/deflation was evaluated on Regional left ventricular dysfunction. Balloon inflation during coronary angioplasty caused profound but reversible regional left ventricular dysfunction in all patients, with 71% developing akinesia or dyskinesia at 60 seconds.
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