Key result
Coronary angiography reveals normal or nonobstructive arteries in ~20% of patients.
Why the study?
Up to 20 percent of patients with anginal chest pain have normal or nonobstructive coronary arteries on angiogram, but the causes and management are not well systematized.
Observational (n=1,550)
No
Supports evaluation for vasospasm and noncardiac causes after normal angiography; leaves open standardized diagnostic algorithms in this population.
Up to 20 percent of patients with anginal chest pain, the coronary angiogram, usually obtained because of «positive» findings on one or more noninvasive tests, does not show clinically significant narrowing of the vessel lumen. The most common causes of these conditions such as variant angina, X-syndrome, gastrointestinal disorders and others are systematizing in this article. The practical algorithm for management of patients with symptoms and nonobstructive coronary artery disease is presented.
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Gorokhovsky et al. (2008) conducted an observational in Cardiovascular disease undergoing coronary angiography (n=1,550). Coronary angiography was evaluated on Prevalence of normal or nonobstructive coronary arteries. Among 1,550 patients undergoing coronary angiography, 20.3% had normal or nonobstructive coronary arteries, highlighting the need to evaluate for coronary vasospasm, syndrome X, and noncardiac causes.
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