Key result
ICD placement and bisoprolol successfully manage syncope in a young adult with arrhythmogenic cardiomyopathy.
Why the study?
Arrhythmogenic ventricular cardiomyopathy is an inherited condition mainly affecting adults and can be challenging to diagnose due to overlapping features with other diseases.
Case Report (n=1)
Single case adds to sparse observational data on ICD use in arrhythmogenic cardiomyopathy; leaves open need for prospective validation before practice change.
Arrhythmogenic ventricular cardiomyopathy is an inherited condition mainly affecting adults. A 35-year-old Asian male patient presented with syncope while walking home. He experienced a number of episodes of light-headedness and dizziness over the past few weeks. A clinical examination found visible injuries to his face and hands. An electrocardiogram showed right axis deviation and right bundle branch block. Echocardiography showed normal biventricular function and the left ventricular ejection fraction was > 55%. A computerized tomography scan of the head and face showed a small fracture to the superior maxillary wall and a computerized tomography pulmonary angiogram demonstrated an inflammatory nodule with right upper and middle lobes changes as well as right hilar lymphadenopathy, suggestive of possible tuberculosis. Blood tests were unremarkable, and troponin was negative. Cardiovascular magnetic resonance imaging showed preserved biventricular function, mild bi-atrial dilatation, and extensive, crescentic-shaped, subepicardial late gadolinium enhancement from basal to apical inferior, basal to apical lateral, and mid to apical anterior segments of the left ventricle suggestive of arrhythmogenic ventricular cardiomyopathy. The patient was commenced on bisoprolol and had an implantable cardioverter defibrillator fitted. He was discharged home with outpatient cardiology follow-up.
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Khan et al. (2023) conducted a case report in Arrhythmogenic Ventricular Cardiomyopathy (n=1). Implantable cardioverter defibrillator and bisoprolol was evaluated. A 35-year-old male presenting with syncope was diagnosed with arrhythmogenic ventricular cardiomyopathy and successfully treated with an implantable cardioverter defibrillator and bisoprolol.
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