Key result
Assessment of heart rate variability and turbulence revealed that patients with very high cardiovascular risk had significantly higher regulatory system strain compared to healthy controls (p<0.01).
Observational (n=922)
Objective of the work is to develop new approaches for prediction, prevention and treatment of complications in patients with high and very high total cardiovascular risk based on the assessment of an impact on heart rate variability and turbulence.Material and methods.This article is an analysis of 922 Holter heart rate monitoring. All patients were divided into groups: 1- patients with coronary heart disease, but without the accompanying risk factors such as — smoking, obesity, metabolic syndrome. Group 2 — patients who have been smoking tobacco for more than 2 years. 3 group — patients with metabolic syndrome and hypertension аnd the control group.Results. On the basis of the assessment of the state of variability and turbulence of the heart rhythm a scale of the risk of occurrence and progression of life-threatening arrhythmias and sudden cardiac death in patients with high and very high cardiovascular risk and patients with cardiovascular diseases was created. Conclusion. Determining the heart rate variability is a simple, not invasive, affordable screening method to forecast the emergency and occurrence of cardiovascular diseases and early detection of patients predisposed to a sudden cardiac death in the general population.
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A. I. Vytryhovskyi (2017) conducted an observational in High and very high cardiovascular risk (n=922). Heart rate variability and turbulence assessment vs. Healthy controls was evaluated on Indicator of Activity of Regulatory Systems (PARS) score (p=<0.01). Assessment of heart rate variability and turbulence revealed that patients with very high cardiovascular risk had significantly higher regulatory system strain compared to healthy controls (p<0.01).
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