Key result
Masked hypertension affects up to ~20% of normotensive youth and links to higher LV mass.
Why the study?
The occurrence and characteristics of masked hypertension in children and adolescents have been investigated in some studies but remain incompletely characterized.
Masked hypertension occurs in ~8-15% of normotensive children; leaves open whether ambulatory monitoring is warranted in obese or diabetic youth.
The occurrence of masked hypertension (MH), that is, normal office but high out-of-office blood pressure (BP) has been investigated in children and adolescents in some studies1–4 using ambulatory BP monitoring. Matsuoka and Awazu1 studied 136 normotensive subjects and found that MH was present in 11% of them. Subjects with MH included those with diabetic nephropathy and obesity.1 Stabouli et al.2 evaluated 53 normotensive subjects and observed MH in 8 (15%) individuals.2 Lurbe et al.3 reported that 45 (7.8%) of 580 normotensive individuals showed MH. Compared with normotensive controls, those with MH were more obese and more likely to have parental history of hypertension.3 Finally, MacNeice et al.4 found MH in 9 (20%) of 44 normotensive subjects. The majority of the abovementioned papers2–4 evaluated target organ status in subjects with MH. Higher left ventricular (LV) mass in MH, when compared to normotension, was reported.2–4 Notably, higher LV mass is associated with increased cardiovascular risk in the adult population.
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Sante Donato Pierdomenico (2009) conducted a review in Masked hypertension. Masked hypertension vs. Normotension was evaluated. Masked hypertension is present in 7.8% to 20% of normotensive children and adolescents and is associated with higher left ventricular mass compared to normotension.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: