Key result
Thermal entrainment HRV frequency response distinguishes patients with cardiovascular symptoms from healthy controls.
Why the study?
Conventional autonomic function tests are not clinically useful for evaluating exaggerated cardiovascular responsiveness in young men with dystonic symptoms and orthostatic intolerance.
Population
7 subjects with cardiovascular symptoms and 7 controls
Comparison
Subjects with dystonic symptoms vs controls
Design
Case-control study using thermal entrainment method
Authors
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May aid autonomic assessment where conventional tests fail in orthostatic intolerance; leaves open clinical utility pending validation.
Case-Control (n=14)
p-value: p=0.008
Lindqvist et al. (1989) conducted a case-control in Cardiovascular symptoms (dystonic symptoms and orthostatic intolerance) (n=14). Thermal entrainment method vs. Healthy controls was evaluated on Frequency response of heart rate variability to thermal stimulation at 0.01, 0.02, 0.03 and 0.1 Hz (p=0.008). A thermal entrainment method demonstrated significantly different frequency responses of heart rate variability between subjects with cardiovascular symptoms and controls (p=0.008).
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