Key result
Post-mortem stereo-arteriography maps coronary occlusions directly to anastomotic enlargement and myocardial damage.
Why the study?
The relationship between anastomotic enlargement and ischemic myocardial damage in coronary artery disease and other heart conditions was not fully characterized.
Population
59 post mortem hearts including 25 with coronary artery disease, 17 with other heart disease, 12 normal, and 5 with increased heart weight
Comparison
Coronary artery disease hearts versus other heart disease and normal hearts
Design
Observational post mortem study using stereo-arteriography and histology
Authors
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Post-mortem arteriography in 59 hearts is hypothesis-generating; prospective studies needed to confirm patterns in living patients.
Observational (n=59)
W. F. M. Fulton (1964) conducted an observational in Coronary artery disease (n=59). Coronary artery occlusion vs. Normal hearts was evaluated on Pattern of anastomotic enlargement and myocardial damage. Post-mortem stereo-arteriography of 59 hearts enabled three-dimensional correlation of coronary occlusive lesions with the extent of myocardial damage and anastomotic enlargement.
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