Key result
Infarct-related artery patency is linked to improved post-MI electrical stability.
Why the study?
Patency of the infarct-related artery after myocardial infarction is suggested to predict survival rates and may confer benefits including electrical stability, but the evidence supporting this is varied and requires review.
Answers are grounded in this paper and cite their sources.
May reduce post-MI arrhythmic death via electrical stability from patent infarct artery; leaves open confirmation in randomized trials.
Arrhythmic events are responsible for the majority of sudden cardiac deaths after myocardial infarction. Many clinical studies have suggested that patency of the infarct-related artery, achieved by thrombolytic therapy or revascularization procedures, is a predictor of survival rates irrespective of myocardial salvage. The open-artery hypothesis suggests that an open infarct-related artery may result in other potential mechanisms, of benefits including electrical stability. This review focuses on the various levels and types of evidence supporting this contention.
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Carnendran et al. (2000) conducted a review in Myocardial infarction. Patency of the infarct-related artery was evaluated on Electrical stability and survival rates. This review summarizes evidence supporting the open-artery hypothesis, suggesting that patency of the infarct-related artery after myocardial infarction may improve electrical stability.
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