Key result
Strain-quantified dobutamine stress echocardiography distinguishes 3 distinct regional ischaemic substrates.
Why the study?
Differentiation between differing regional ischaemic substrates is crucial for decision-making in patients with coronary artery disease.
Observational
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Strain quantification on dobutamine stress echocardiography may differentiate ischaemic substrates; leaves open clinical adoption pending prospective validation.
The differentiation between differing regional ischaemic substrates is crucial for decision-making in patients with coronary artery disease. This study demonstrates that quantification of dobutamine stress echocardiography using ultrasonic strain measurement has the potential to identify three differing regional ischaemic substrates (ischaemic, stunned and scarred) in the same patient. The data were validated by traditional analysis of dobutamine stress echo, coronary angiography and correlative quantitative positron emission tomography information.
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Kowalski et al. (2003) conducted an observational in Coronary artery disease. Ultrasonic strain measurement during dobutamine stress echocardiography vs. Traditional analysis, coronary angiography, and positron emission tomography was evaluated on Identification of differing regional ischaemic substrates (ischaemic, stunned and scarred). Quantification of dobutamine stress echocardiography using ultrasonic strain measurement identified three differing regional ischaemic substrates (ischaemic, stunned, and scarred).
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