Key result
Exercise-induced cardiac arrest highlights hidden aortic stenosis risk in young patients with bicuspid aortic valves.
Why the study?
Bicuspid aortic valve is a common congenital defect that predisposes to valve dysfunction and aortopathy, with diagnostic criteria for severe aortic stenosis established by flow measurements.
Case Report (n=1)
Highlights the risk of exercise-induced cardiac arrest in young patients with bicuspid aortic valve and severe aortic stenosis.
Supports awareness of severe aortic stenosis risk during exercise in young bicuspid aortic valve patients; leaves open need for larger studies.
Bicuspid aortic valve (BAoV) is the most common congenital heart defect, with a prevalence of 0.77% in newborns. Bicuspid aortic valve predisposes individuals to valve dysfunction and aortopathy.1 Routine evaluation of patients with BAoV consists of electrocardiogram, echocardiogram, and clinical examination. When flow conditions are normal, concordant severe aortic stenosis (AS) can be diagnosed when the mean gradient is ≥40 mm Hg or the peak velocity is ≥4.0 m/s and the aortic valve (AoV) area is ≤1.0 cm2.
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Rasmussen et al. (2026) conducted a case report in Bicuspid aortic valve and aortic stenosis (n=1). A young man with a bicuspid aortic valve experienced exercise-induced cardiac arrest, highlighting the hidden danger of aortic stenosis in this population.
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