Key result
Fragmented RV potentials in ARVC trigger inappropriate ICD shock via failed morphology discrimination.
Why the study?
ARVC is characterized by RV structural abnormalities and fatal arrhythmias, and ICD therapy, while preventing sudden cardiac death, carries risks of device-related complications including inappropriate shocks.
Case Report (n=1)
In ARVC with extensive RV disease, morphology discrimination may fail and trigger inappropriate shocks; leaves open need for tailored sensing algorithms.
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a cardiac inherited disease characterized by the presence of right ventricle (RV) structural abnormalities and fatal arrhythmias arising from an abnormal RV, which can lead to sudden cardiac death.1–3 Implantable cardioverter-defibrillator (ICD) therapy not only enables an effective prevention of sudden cardiac death related to lethal arrhythmias but is also associated with the risk of device-related complications, including device infections, inappropriate shocks, loss of ventricular sensing, and other lead-related complications.
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Goto et al. (2022) conducted a case report in Arrhythmogenic right ventricular cardiomyopathy (ARVC) (n=1). Implantable cardioverter-defibrillator (ICD) was evaluated on Inappropriate ICD shock. A 72-year-old man with arrhythmogenic right ventricular cardiomyopathy experienced an inappropriate ICD shock because fragmented potentials from an extensively diseased right ventricle caused the QRS morphology-based discrimination algorithm to fail.
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