Why the study?
The relationship between lifestyle factors and HDL cholesterol subfraction levels among healthy adults was not well characterized.
Cross-Sectional (n=227)
No
p-value: p=<0.05
Serum levels of total high-density lipoprotein cholesterol (HDL-C) and its subfractions (HDL2-Cand HDL3-C) were measured in 227 healthy Japanese adults. These values were related to a number of lifestyle factors.On co-variance analysis, alcohol drinking had an independent contribution to HDL-C and HDL3-C (p<0.05) in males. Cigarette smoking showed no association with subfractions of HDL-C in males. Three physical activities-sport, work and leisure time activity-had no significant association with subfractions of HDL-C. The degree of obesity as expressed by body mass index (BMI) was significantly negatively related (p<0.05) to HDL-C and HDL2-C levels among females. Among males, although a trend test showed no statistically significant relation to BMI, HDL-C and HDL2-C levels were significantly higher (p<0.05) in the normal group (20≤BMI<25) than in the obese group (BMI≥25).
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Momose et al. (1994) conducted a cross-sectional in Healthy adults (n=227). Lifestyle factors (alcohol, smoking, physical activity, obesity) vs. Reference categories (e.g., non-drinkers, normal BMI) was evaluated on Serum levels of total HDL-C and its subfractions (HDL2-C and HDL3-C) (p=<0.05).
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