Key result
In end-stage renal disease patients on maintenance haemodialysis, an average of 42% had adequate blood pressure control, with no correlation found between the number of drugs used and blood pressure control.
Why the study?
Hypertension is a major cardiovascular risk factor in CKD patients on maintenance haemodialysis, but data on antihypertensive drug use and blood pressure control in this population are limited.
Observational (n=50)
No
Answers are grounded in this paper and cite their sources.
In patients on maintenance hemodialysis, hypertension is frequently uncontrolled and is most effectively managed through a combination of targeted dry weight reduction and specific antihypertensive combinations like amlodipine and clonidine.
A longitudinal study done on 50 CKD patients on maintenance haemodialysis on antihypertensive drugs. Hypertension in patients affected by CKD has been recognized as one of the major classical cardiovascular risk factors. The study aims to describe the class and number of drugs used for management of hypertension in patients on maintenance haemodialysis and to measure blood pressure and assess how many patients have achieved target blood pressure. On an average 42% of patients had adequate BP control and 58% were found not to have adequate BP control. The most commonly used antihypertensive BP medications being calcium channel blockers- amlodipine and alpha agonist clonidine followed by beta blockers- metoprolol and the most frequently used drug combination being amlodipine with clonidine. Weight reduction to achieve adequate dry weight for adequate BP control was found to be at range of 2-3kgs.
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Antony et al. (2018) conducted an observational in Chronic Kidney Disease (CKD) on maintenance haemodialysis with hypertension (n=50). Antihypertensive drugs was evaluated on Adequate blood pressure control. In end-stage renal disease patients on maintenance haemodialysis, an average of 42% had adequate blood pressure control, with no correlation found between the number of drugs used and blood pressure control.
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