What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Hypertension (n=100). Intervention: Antihypertensive drugs. Primary outcome: Appropriateness of antihypertensive drug use (right patient, right indication, right drug, and right dose).

What does this research mean for the field?

Inpatient antihypertensive therapy demonstrates high guideline appropriateness, with 100% correct patient selection, 98% correct indication, 90% correct drug choice, and 97% correct dosing in a hospital cohort. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the appropriateness of antihypertensive drug therapy based on right patient, right indication, right drug, and right dosage criteria among hospitalized patients.

October 7, 2026Jurnal Ilmiah Kesehatan Ar-Rum SalatigaOpen Access

Evaluasi Ketepatan Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Rawat Inap Di Rsud Salatiga Tahun 2023

Q: What are the key findings of this study?

Retrospective evaluation of antihypertensive prescriptions in 100 inpatients demonstrated 100% correct patient, 98% correct indication, 90% correct medication, and 97% correct dosage.

View Full Paper

Ask AI

Bookmark

Key result

Inpatient antihypertensive prescribing achieves ~90% guideline-appropriate drug selection in cross-sectional evaluation.

n=100

Why the study?

Hypertension requires appropriate medication use to ensure effective treatment and minimize therapy failure, but the accuracy of antihypertensive drug use in inpatient settings needed evaluation.

Key Points

To evaluate the appropriateness of antihypertensive drug therapy based on right patient, right indication, right drug, and right dosage criteria among hospitalized patients.
Conducted a retrospective cross-sectional descriptive analytical study reviewing medical records of N=100 hospitalized hypertensive patients admitted between January and December 2023 at RSUD Salatiga.
Evaluated prescribing appropriateness against guidelines from the Indonesian Ministry of Health (Kemenkes RI 2019), DiPiro (2015), and the International Society of Hypertension (ISH 2020).
Achieved prescribing appropriateness rates of 100% for right patient, 98% for right indication, 90% for right drug, and 97% for right dose.
Combination therapy was administered in 82% of patients compared with monotherapy in 18%, with candesartan being the most frequently prescribed drug (44%, n=87), followed by amlodipine (39%, n=77).
Observed that 53% of patients were female and 55% were aged <60 years.

Study Design

Type

Cross-Sectional (n=100)

Multicenter

Structured PICO

Population

100 hospitalized patients with hypertension at RSUD Salatiga, 53% female, whose medical records were retrospectively analyzed for antihypertensive treatment appropriateness.

Exposure

Antihypertensive drug therapy (82% received combination therapy, most commonly candesartan and amlodipine).

Outcome

Accuracy of medication use based on right patient, right indication, right drug, and right dose, evaluated against Indonesian Ministry of Health 2019, DiPiro IX 2015, and ISH 2020 guidelines.

Inpatient prescribing of antihypertensive medications at a single center in Indonesia showed high compliance with guidelines, with accuracy rates of 90% or higher across indication, drug selection, and dosing.

Limitations

Differences between treatment guidelines used by prescribing physicians and those used by researchers for evaluation may have affected the medication appropriateness scores.

Implication

Supports high local guideline adherence in Indonesian inpatients; leaves open generalizability and prospective validation.

Abstract

Hipertensi merupakan kondisi penyakit akibat tekanan darah di atas batas normal, ditandai dengan meningkatnya tekanan darah sistolik ≥140 mmHg dan tekanan darah diastolik ≥90 mmHg (Tuloli, 2021). Penyakit hipertensi memerlukan pengobatan dengan tepat supaya efektif dan meminimalkan kegagalan terapi. Penelitian ini bertujuan untuk menggambarkan penggunaan obat antihipertensi dan ketidaktepatan pengobatan berdasarkan tepat pasien, tepat indikasi, tepat obat, dan tepat dosis. Metode yang digunakan yaitu deskriptif analitik dengan rancangan cros sectional, pengambilan data secara retrospektif di rekam medis sejumlah 100 pasien sebagai sampel. Kemudian dianalisis menggunakan parameter Kemenkes RI tahun 2019, DiPiro IX tahun 2015, ISH tahun 2020. Hasil penelitian menunjukkan pasien jenis kelamin terbanyak yaitu perempuan (53%), pasien menderita hipertensi paling banyak usia 60 tahun (55%), terapi yang sering digunakan yaitu terapi kombinasi (82%), obat yang paling sering diresepkan yaitu candesartan (44%). Hasil evaluasi dari penelitian ini diperoleh tepat pasien 100%, 98% tepat indikasi, 90% tepat obat, dan 97% tepat dosis.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Sutarmanto et al. (2025) conducted a cross-sectional in Hypertension (n=100). Antihypertensive drugs was evaluated on Appropriateness of antihypertensive drug use (right patient, right indication, right drug, and right dose). Retrospective evaluation of antihypertensive prescriptions in 100 inpatients demonstrated 100% correct patient, 98% correct indication, 90% correct medication, and 97% correct dosage.

synapsesocial.com/papers/6ac591f938c9af7ead3834dd https://doi.org/10.36409/jika.v9i2.256

View Full Paper

Ask AI

Bookmark

Implication

Supports high local guideline adherence in Indonesian inpatients; leaves open generalizability and prospective validation.

Evaluasi Ketepatan Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Rawat Inap Di Rsud Salatiga Tahun 2023

Key Points

Study Design

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Evaluasi Ketepatan Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Rawat Inap Di Rsud Salatiga Tahun 2023

Key Points

Study Design

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading