Key result
Surgical management of functional mitral regurgitation in heart failure lacks randomized trial support.
Why the study?
Surgical management of mitral valve regurgitation in heart failure patients remains controversial due to lack of prospective randomized controlled trials clarifying indications and strategies.
Surgery for functional MR in HF should not be routine absent RCTs; leaves open optimal strategy pending prospective trials.
Relevant secondary mitral regurgitation occurs in 35-50% of patients with chronic heart failure and is associated with increased mortality.Surgical management of patients with mitral valve regurgitation and heart failure remains controversial.There are several questions which are not sufficiently clarified because of a lack of prospective randomised controlled trials: (1.)The indication for concomitant mitral valve surgery in patients undergoing coronary artery bypass grafting (CABG) with moderate to severe mitral valve regurgitation; (2.) the management of functional mitral valve regurgitation; (3.) the appropriate surgical strategy: repair or chordal-sparing replacement.
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A 2013 study conducted a review in Chronic heart failure with functional mitral regurgitation. Surgical management (repair or replacement) was evaluated. Surgical management of functional mitral regurgitation in heart failure remains controversial due to a lack of prospective randomized controlled trials.
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