Key result
IV insulin monotherapy cuts serum triglycerides ~90%, achieving complete clinical recovery.
Why the study?
No specific therapeutic guidelines exist for severe hypertriglyceridemic pancreatitis and there is a paucity of literature comparing different treatment modalities.
Comparison
Insulin monotherapy as treatment for hypertriglyceridemic pancreatitis
Design
Case report
Authors
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May support insulin in refractory hypertriglyceridemia; hypothesis-generating and requires prospective validation.
Case Report (n=1)
No
Inayat et al. (2018) conducted a case report in Hypertriglyceridemic pancreatitis (n=1). Insulin infusion was evaluated on Reduction in serum triglyceride levels and symptom resolution. Intravenous insulin monotherapy successfully reduced serum triglyceride levels from 5047 mg/dL to less than 500 mg/dL over 12 days, resulting in complete clinical recovery.
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