Key result
Bilateral total thoracoscopic atrial ablation was shown to be a safe and effective procedure that improves left ventricular function and restores sinus rhythm in patients with reduced ejection fraction.
Central MessageBilateral thoracoscopic atrial ablation in patients with reduced ejection fraction can improve ventricular function and restore sinus rhythm.See Article page 60. Bilateral thoracoscopic atrial ablation in patients with reduced ejection fraction can improve ventricular function and restore sinus rhythm. See Article page 60. Kim and colleagues1Kim H.R. Jeong D.-S. Kwon H.-J. Park S.-J. Park K.-M. Kim J.S. et al.Total thoracoscopic ablation in patients with atrial fibrillation and left ventricular dysfunction.J Thorac Cardiovasc Surg Tech. 2021; 8: 60-66Scopus (2) Google Scholar present a series of 31 patients with reduced ejection fraction and persistent atrial fibrillation (AF) undergoing bilateral total thoracoscopic atrial ablation (TTA) (Figure 1). The authors concluded that TTA is a safe and effective procedure that improves left ventricular function and restores sinus rhythm in patients with AF and left ventricular dysfunction. This is neither the first report of TTA,2van Laar C. Kelder J. van Putte B.P. The totally thoracoscopic maze procedure for the treatment of atrial fibrillation.Interact Cardiovasc Thorac Surg. 2017; 24: 102-111Crossref PubMed Scopus (26) Google Scholar nor is it the first report of surgical AF ablation in patients with reduced ejection fraction.3Stulak J.M. Dearani J.A. Daly R.C. Zehr K.J. Sundt III, T.M. Schaff H.V. Left ventricular dysfunction in atrial fibrillation: restoration of sinus rhythm by the Cox-maze procedure significantly improves systolic function and functional status.Ann Thorac Surg. 2006; 82: 494-500Abstract Full Text Full Text PDF PubMed Scopus (73) Google Scholar However, this may be one of the first series of TTA in patients with reduced ejection fraction. While the series is small, the follow-up is good. The illustrative video is helpful. These data reinforce the few studies of TTA and the few studies of surgical ablation in reduced ejection fraction. This study does have limitations. First, this is a retrospective clinical series with echocardiography and rhythm assessment at irregularly timed intervals. Also of note, 8 of 31 patients did receive additional catheter ablation after the initial TTA procedure. Results are presented for all 31 patients after the last performed procedure, emphasizing the value of combined transcatheter and thoracoscopic approaches in some patients. Thoracoscopy is not likely to replace catheter ablation, given the additional morbidity of surgical TTA over a transcatheter procedure. However, these data and others suggest that TTA may be a reasonable alternative to transcatheter ablation in patients who are low risk or who have failed transcatheter ablation or who may have other risk factors for transcatheter ablation failure, such as persistent AF. Thoracoscopic and other epicardial approaches do have advantages of access to some of the epicardial ganglion plexuses, which may be important in certain patients. Epicardial approaches can also provide access to externally occlude the left atrial appendage.4Franciulli M. De Martino G. Librera M. Desoky A. Mariniello A. Iavazzo A. et al.Stand-alone thoracoscopic left atrial appendage closure in nonvalvular atrial fibrillation patients at high bleeding risk.Innovations (Phila). 2020; 15: 541-546Crossref PubMed Scopus (2) Google Scholar In short, combined thoracoscopic and transcatheter approaches may be complementary. Other less-invasive surgical approaches such as the transpericardial convergent procedure5DeLurgio D.B. Crossen K.J. Gill J. Blauth C. Oza S.R. Magnano A.R. et al.Hybrid convergent procedure for the treatment of persistent and long-standing persistent atrial fibrillation: results of CONVERGE clinical trial.Circ Arrhythm Electrophysiol. 2020; 13: e009288Crossref PubMed Scopus (19) Google Scholar may share with TTA the advantages and disadvantages of an epicardial approach over transcatheter endocardial procedures. Thus, Kim and colleagues show that TTA can be safe and effective in patients with reduced ejection fraction. Thoracoscopic ablation may have a role, even for the faint of heart. Total thoracoscopic ablation in patients with atrial fibrillation and left ventricular dysfunctionJTCVS TechniquesVol. 8PreviewTo evaluate the effectiveness and safety of totally thoracoscopic ablation (TTA) in patients with left ventricular (LV) dysfunction for treatment of atrial fibrillation (AF) refractory to antiarrhythmic drug (AAD) therapy. Full-Text PDF Open Access
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Donald Duane Glower (2021) conducted an editorial in Reduced ejection fraction and persistent atrial fibrillation (n=31). Bilateral total thoracoscopic atrial ablation (TTA) was evaluated on Improvement in left ventricular function and restoration of sinus rhythm. Bilateral total thoracoscopic atrial ablation was shown to be a safe and effective procedure that improves left ventricular function and restores sinus rhythm in patients with reduced ejection fraction.
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