Key result
Totally thoracoscopic ablation achieves ~94% sinus rhythm in refractory AF with LV dysfunction.
Why the study?
The effectiveness and safety of totally thoracoscopic ablation for drug-refractory AF in patients with left ventricular dysfunction needed evaluation.
Does totally thoracoscopic ablation (TTA) improve rhythm outcomes in patients with drug-refractory atrial fibrillation and left ventricular dysfunction?
Cohort (n=31)
Does totally thoracoscopic ablation (TTA) improve rhythm outcomes in patients with drug-refractory atrial fibrillation and left ventricular dysfunction?
Totally thoracoscopic ablation appears effective in restoring sinus rhythm in patients with drug-refractory atrial fibrillation and left ventricular dysfunction.
TTA may support rhythm control evaluation in this population; leaves open confirmation versus catheter ablation or medical therapy in RCTs.
OBJECTIVE: To evaluate the effectiveness and safety of totally thoracoscopic ablation (TTA) in patients with left ventricular (LV) dysfunction for treatment of atrial fibrillation (AF) refractory to antiarrhythmic drug (AAD) therapy. METHODS: Between January 2012 and December 2018, 31 patients underwent TTA with drug-refractory AF and preoperative left ventricular ejection fraction (LVEF) <50% were included. Of the 31 patients, 8 received additional catheter ablation with an electrophysiologic study within 3 months after TTA. The rhythm outcome was obtained by 12-lead electrocardiography or 24-hour Holter monitoring. The rate of sinus rhythm state was 93.5% (29 of 31), and freedom from arrhythmias off AADs after the final procedure was 61.3% (19 of 31) at a median follow-up of 32 months (IQR, 24-54 months). CONCLUSIONS: TTA is a safe and effective procedure that improves LV function and restores sinus rhythm in AF patients with LV dysfunction.
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Kim et al. (2021) conducted a cohort in Atrial fibrillation with left ventricular dysfunction (n=31). Totally thoracoscopic ablation (TTA) was evaluated on Rate of sinus rhythm state. Totally thoracoscopic ablation in patients with drug-refractory atrial fibrillation and left ventricular dysfunction achieved a 93.5% rate of sinus rhythm at a median follow-up of 32 months.
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