Key result
Totally thoracoscopic ablation shows ~60% freedom from atrial arrhythmia recurrence at four years.
Why the study?
Evidence for long-term rhythm control and stroke reduction following totally thoracoscopic ablation for drug- or catheter-refractory symptomatic AF is limited.
Does totally thoracoscopic ablation improve freedom from atrial arrhythmia recurrence in patients with symptomatic refractory atrial fibrillation?
Observational (n=82)
No
Does totally thoracoscopic ablation improve freedom from atrial arrhythmia recurrence in patients with symptomatic refractory atrial fibrillation?
Totally thoracoscopic ablation provides sustainable long-term rhythm control and low stroke rates in patients with refractory atrial fibrillation.
Supports durable rhythm control with low stroke rates in refractory AF; leaves open randomized comparisons to catheter ablation.
Introduction Totally thoracoscopic ablation for symptomatic atrial fibrillation (AF) refractory to drug or catheter based therapy is indicated as a Class 2A recommendation according to latest guidelines. Evidence for long‐term rhythm control and stroke reduction is limited. The aim of this study was to report on long‐term outcome after totally thoracoscopic ablation. Methods and Results In total 82 consecutive patients were included that underwent totally thoracoscopic ablation including left appendage closure (2012‐2013). The primary outcome was freedom from atrial arrhythmia recurrence. Secondary outcomes were survival, freedom from cerebrovascular events, freedom from reablation and definite pacemaker implantation. The mean age was 59.9 ± 8.6 years and 71% were male. The mean CHA2DS2‐VASc score was 1.2 ± 1.0. The overall freedom from atrial arrhythmia was 60% after a mean follow up of 4.0 ± 0.6 years. Freedom from cerebrovascular events was 98.8% after mean follow‐up of 4.4 ± 0.3 years and overall survival was 98.8%, with one noncardiac related death. The observed rate of ischemic stroke, hemorrhagic stroke or transient ischemic attack was 0.3 per 100 patient‐years. Conclusions Totally thoracoscopic ablation is an effective sustainable rhythm control therapy for AF with a reasonable recurrence rate and low stroke rate when performed in dedicated AF centers.
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Vos et al. (2019) conducted an observational in Symptomatic drug-refractory atrial fibrillation (n=82). Totally thoracoscopic ablation was evaluated on Freedom from atrial arrhythmia recurrence (AF, atrial flutter, or atrial tachyarrhythmia >30 seconds). Totally thoracoscopic ablation resulted in a 60% freedom from atrial arrhythmia recurrence after a mean follow-up of 4.0 years, with an observed stroke rate of 0.3 per 100 patient-years.
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