Key result
Cardiac rehabilitation cuts rehospitalization odds ~68% and improves LVEF in elderly heart failure.
Why the study?
The clinical efficacy of cardiac rehabilitation on elderly patients with chronic heart failure was not systematically evaluated.
Meta-Analysis (n=1,782)
Odds Ratio: 0.32 (95% CI 0.21–0.49)
p-value: p=<0.000001
Supports routine cardiac rehabilitation referral for elderly chronic HF; extends prior evidence to this population.
AIMS: The purpose of this study was to investigate the effects of cardiac rehabilitation (CR) on elderly patients with Chronic heart failure (CHF) by literature search and meta-analysis. METHODS: We conducted an electronic search on PubMed, Cochrane Library, Embase, CNKI, Wanfang, and VIP database platforms. The search period was from the establishment of the database to November 2021 for randomized controlled studies (RCTs) related to the effects of CR on elderly patients with CHF. The RevMan 5.4 was used for meta-analysis. RESULTS: This study included 16 articles involving a total of 1782 patients, including 892 in the CR group and 890 in the control group. Meta-analysis showed that compared with conventional interventions, CR increased left ventricular ejection fraction in elderly patients with CHF [mean difference (MD):5.73,95% confidence interval (CI):2.05 to 9.40,Z = 3.05,P = 0.002], and decreased left ventricular end-diastolic diameter in elderly patients with CHF (MD:-4.82,95%CI:-7.49 to 15,Z = 3.54,P = 0.0004), increased the 6-minute walk test distance (MD:62.66,95% CI:44.40 to 80.92,Z = 6.72,P<0.00001), decreased the rehospitalization rate (OR:0.32,95%) CI: 0.21 0.49, Z = 5.33, P < 0.000001). CONCLUSIONS: CR can improve cardiac function, prognosis and reduce rehospitalization rate of elderly patients with CHF.
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Chen et al. (2022) conducted a meta-analysis in Chronic heart failure (n=1,782). Cardiac rehabilitation vs. Conventional treatment was evaluated on Rehospitalization rate (OR 0.32, 95% CI 0.21-0.49, p=<0.000001). Cardiac rehabilitation significantly decreased the odds of rehospitalization (OR 0.32) and improved left ventricular ejection fraction compared to conventional treatment in elderly patients with chronic heart failure.
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