Cell therapy of a chronic continuous form of ulcerative colitis with severe activity with autological multipotent mesenchymal stromal cells: analysis of the clinical case

Ulcerative colitis is an inflammatory disease of the mucosa of the colon and rectum. The clinical practice of cell therapy programs based on mesenchymal stem cells allows to limit patient data on the use of hormonal or immunosuppressive drug therapy. The article presents a clinical case of 52 years man with ulcerative colitis, which was treated by autologous multipotent mesenchymal stromal cells that pass through the inferior mesenteric artery. Treatment control was carried out 43 days after the procedure. The following results were obtained: a decrease in the diseases activity index with a severe degree (DAI = 9) to mild (DAI = 4), refusal of steroid therapy, patient satisfaction according to SF-36 questionnaire and diary.