Microsporidiosis Myositis in a Patient with the Acquired Immunodeficiency Syndrome

Brief Reports1 May 1985Microsporidiosis Myositis in a Patient with the Acquired Immunodeficiency SyndromeDENNIS K. LEDFORD, M.D., MARK D. OVERMAN, M.D., AMERICO GONZALVO, M.D., ANN CALI, Ph.D., STEPHEN W. MESTER, M.D., RICHARD F. LOCKEY, M.D.DENNIS K. LEDFORD, M.D., MARK D. OVERMAN, M.D., AMERICO GONZALVO, M.D., ANN CALI, Ph.D., STEPHEN W. MESTER, M.D., RICHARD F. LOCKEY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-102-5-628 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWe report the first case of a patient with the acquired immunodeficiency syndrome with myositis secondary to a microsporidan infection. Microsporida are ubiquitous spore-forming protozoans that most commonly infect arthropods and fish but also can infect other invertebrates and vertebrates including mammals (1, 2).A 20-year-old black man had had progressive generalized muscle weakness with contractures for 7 months and fever, generalized lymphadenopathy, and an 18-kg weight loss over the last 5 months. He admitted to having had one homosexual contact (passive oral-genital) 1 year before admission. His close friends, including a female sexual partner; his family; and the previous...References1. KREIER J ed. Parasitic Protozoa. Vol. 4. New York: Academic Press, Inc.; 1977:155-96. Google Scholar2. NOBLE E and NOBLE G eds. Parasitology: The Biology of Animal Parasitism. 5th ed. Philadelphia: Lea & Febiger; 1982:114-8. Google Scholar3. STRANO A, CALI A, and NEAFIE R. Microsporidiosis. In: BINFORD CH, CONNOR DH, eds. Pathology of Tropical and Extraordinary Diseases. Washington, D.C.: Armed Forces Institute of Pathology; 1976:336-9. Google Scholar4. WOLF A and COWEN D. Granulomatous encephalomyelitis due to an Encephalitozoon (encephalitozoic encephalomyelitis). Bull Neurol Inst NY. 1937;6:306-71. Google Scholar5. MATSUBAYASHI H, KOIKE T, and MIKATA I. A case of encephalitozoon-like body infection in man. Arch Pathol. 1959;67:181-7. Google Scholar6. SHADDUCK J, WATSON W, PAKES S, and CALI A. Animal infectivity of Encephalitozoon cuniculi. J Parasitol. 1979;65:123-9. CrossrefMedlineGoogle Scholar7. MARGILETH A, STRANO A, CHANDRA R, NEAFIE R, BLUM M, and MCCULLY R. Disseminated nosematosis in an immunologically compromised infant. Arch Pathol. 1974;95:145-50. Google Scholar8. ASHTON N and WIRASINHA P. Encephalitozoonosis (nosematosis) of the cornea. Br J Ophthalmol. 1973;57:669-74. CrossrefMedlineGoogle Scholar9. PINNOLIS M, EGBERT P, FONT R, and WINTER F. Nosematosis of the cornea: case report, including electron microscopic studies. Arch Ophthalmol. 1981;99:1044-7. CrossrefMedlineGoogle Scholar10. MARCUS P, VAN DER WALT J, and BURGER P. Human tumor microspridosis:first reported case. Arch Pathol. 1973;95:341-3. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DENNIS K. LEDFORD, M.D.; MARK D. OVERMAN, M.D.; AMERICO GONZALVO, M.D.; ANN CALI, Ph.D.; STEPHEN W. MESTER, M.D.; RICHARD F. LOCKEY, M.D.Affiliations: University of South Florida, Tampa, Florida Rutgers University Newark, New Jersey. 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SCHIFF, M.D.Myositis and acquired immunodeficiency syndromeSelective Expansion of a CD3+CD4-CD8- Subpopulation in Clinical Groups Associated with Human Immunodeficiency Virus InfectionAspergillus myositis in a patient with a myelodysplastic syndrome 1 May 1985Volume 102, Issue 5Page: 628-630KeywordsAIDSAntibodiesHIVMicrosporidiosisMusclesMyositisProtozoan infectionsProtozoansPyrimethamineWeight loss ePublished: 1 December 2008 Issue Published: 1 May 1985 PDF downloadLoading ...