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The extract of Talaromyces flavus IFM52668 showed the characteristic antifungal activity against Aspergillus fumigatus. In the course of a search for the active compounds, funicone, vermistatin, and a new funicone derivative, 9,14-epoxy-11-deoxyfunicone, were isolated along with emerin. The structure of 9,14-epoxy-11-deoxyfunicone was determined from the analysis of the spectroscopic investigation. The antifungal activity of the compounds was discussed.
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Komai et al. (2004) studied this question.
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