Why the study?
The optimal heart rate target in patients with heart failure in sinus rhythm is unknown and needs to be defined to improve prognosis.
Does lowering resting heart rate to below 70/min improve outcomes in patients with heart failure in sinus rhythm?
Does lowering resting heart rate to below 70/min improve outcomes in patients with heart failure in sinus rhythm?
Lowering resting heart rate to below 70/min is beneficial in heart failure patients in sinus rhythm, but excessive reductions do not appear to offer further clinical advantages.
May support <70 bpm target in HF sinus rhythm; leaves open whether stricter reductions add benefit.
The incidence of heart failure in the Polish population ranges from 1.0 to 1.3 million cases. Although the optimal heart rate is unknown, it should be sought to exceed 70/min. A higher heart rate increases the risk of death, arrhythmic events, and hospitalization due to deterioration of heart function. The association of increased heart rate with deterioration of long-term prognosis applies to both patients with reduced and preserved ejection fraction. In patients with heart failure, the resting heart rate should be lowered to below 70/min. Patients with the greatest reduction in heart rate within 3 months of hospitalization due to deterioration of heart function are particularly beneficial. It seems that lowering the resting frequency to < 65/min and reducing it of more than 20/min do not bring any additional benefits.
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Przemyslaw P. Mitkowski (2024) conducted a review in Heart failure in sinus rhythm. Heart rate reduction (target < 70/min) was evaluated.
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