Key result
Hypertension is linked to ~4-fold higher stroke odds in a case-control study.
Why the study?
Various factors contribute to ischemic stroke, but the specific contributions of hypertension, diabetes mellitus, and hypercholesterolemia require clarification.
Do hypertension, diabetes mellitus, and hypercholesterolemia increase the risk of stroke in adults >40 years old?
Case-Control (n=152)
No
Do hypertension, diabetes mellitus, and hypercholesterolemia increase the risk of stroke in adults >40 years old?
Odds Ratio: 3.986
Hypertension and hypercholesterolemia are strongly associated with increased stroke risk in this Indonesian population, emphasizing the importance of active primary prevention and risk factor modification.
Hypertension and hypercholesterolemia warrant attention in stroke risk assessment; leaves open diabetes association in this observational cohort.
Stroke is a cerebrovascular disease caused by blockage or rupture of blood vessels in certain parts of the brain. Various factors can cause ischemic stroke. This study aims to determine the contribution of hypertension, diabetes mellitus, and hypercholesterolemia to the incidence of stroke. This type of study uses a Case-Control design. The respondents of this study were 152 respondents, sampling using a purposive sampling technique. Respondents of patients with conditions suspected of having a stroke based on the symptoms that appear who treated at the Kendari City Hospital. Data collection used measuring instruments (tension meter and easy touch). Data analysis was carried out using univariate and bivariate analysis tests. The results showed that hypertension, diabetes mellitus, and hypercholesterolemia were risk factors for stroke with an estimated value of hypertension = 3.986, diabetes mellitus = 0.289, and hypercholesterolemia = 1.699. Recommendation: Hypertension, diabetes mellitus, and hypercholesterolemia are risk factors for stroke, so it is very important for nurses to provide education to the community so that they can control blood pressure, blood glucose levels, and cholesterol to prevent stroke.
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Heltty et al. (2025) conducted a case-control in Ischemic Stroke (n=152). Hypertension vs. Absence of hypertension was evaluated on Incidence of stroke (OR 3.986). Hypertension (OR 3.986) and hypercholesterolemia (OR 1.699) were significant risk factors for the incidence of stroke, whereas diabetes mellitus was not associated with an increased risk.
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