Key result
Novel cardiovascular bond-graph model successfully simulates flow-induced body motions for noninvasive heart output analysis.
Why the study?
A flexible and anatomically detailed model of the human cardiovascular system was needed to simulate body motions caused by blood flow and explore ballistocardiography as a noninvasive measure of heart output.
Bond graph cardiovascular models aid hemodynamic research; leaves open clinical translation pending validation.
Bond graphs have been used to construct a distributed-parameter model of the human cardiovascular system. The model includes the heart and arterial, capillary, and venous segments of both the pulmonary and systemic circulations. Anatomical and physiological data were utilized in implementing the model on a large digital computer. Comparisons of simulated output and measured responses are shown. Because a general-purpose bond graph simulation language for distributed-parameter systems was used, this cardiovascular simulation retains considerable flexibility and can be modified to suit the application. One such application that has been investigated in detail is the simulation of the body motions caused by blood flow in a subject mechanically isolated from the earth. This measurement, the ballistocardiogram (BCG) holds the possibility of a noninvasive means of determining heart output.
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Auslander et al. (1972) studied this question. Bond graph model of the human cardiovascular system was evaluated. A distributed-parameter model of the human cardiovascular system using bond graphs successfully simulated body motions caused by blood flow, demonstrating potential for noninvasive heart output analysis.
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