Key result
HIV infection is linked to increased cardiovascular risk driven by chronic inflammation and antiretroviral-related metabolic changes.
Why the study?
Cardiovascular disease has become a significant cause of morbidity and mortality in people living with HIV despite low absolute risk, driven by higher prevalence of traditional risk factors and effects of HIV and antiretroviral therapy.
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Massmann et al. (2022) conducted a review in HIV infection. HIV infection and Antiretroviral therapy vs. Uninfected general population was evaluated. Cardiovascular risk in people living with HIV is increased compared to uninfected individuals due to a combination of traditional risk factors, immune activation, and metabolic changes related to antiretroviral therapy.
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