Key result
Presumed LV thrombus rapidly resolves within ~5 days, likely driven by spontaneous fibrinolysis.
Why the study?
The rapid disappearance of left ventricular mass presumed to be thrombus in cardiomyopathy patients and its underlying mechanism is not well understood.
Case Report (n=1)
May support fibrinolysis resolving LV thrombus in cirrhosis; hypothesis-generating and should not change practice.
A man aged 41 years with a clinical diagnosis of cardiomyopathy and hepatic insufficiency was found, on angiocardiography, to have a mass, presumably a thrombus, within the left ventricle. A second angiocardiogram performed five days later showed that the thrombus had disappeared. The mechanism invoked was more probably an increase of spontaneous fibrinolysis as described in cirrhotic patients, perhaps helped by heparin, rather than ejection of the mass from the ventricle with silent embolisation somewhere in the systemic circulation.
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Bensaïd et al. (1982) conducted a case report in Cardiomyopathy and hepatic insufficiency with left ventricular mass (n=1). Spontaneous fibrinolysis / Heparin was evaluated on Disappearance of the left ventricular mass on angiocardiography. A presumed left ventricular thrombus rapidly disappeared within 5 days in a 41-year-old man with cardiomyopathy, likely due to spontaneous fibrinolysis associated with hepatic insufficiency.
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