Key result
Sex-specific differences alter echocardiographic cardiac dimensions and volume indices in Weimaraners.
Why the study?
Reference values for echocardiographic variables may differ among dog breeds, and breed-specific values are important for Weimaraners due to their predisposition to dilated cardiomyopathy.
Cross-Sectional (n=339)
Yes
p-value: p=<0.001
This study establishes the first comprehensive breed- and sex-specific echocardiographic reference intervals for clinically healthy Weimaraner dogs, which will facilitate the accurate diagnosis of early cardiac disease such as dilated cardiomyopathy.
May support sex-specific echocardiographic references in Weimaraners; leaves open prospective validation before clinical adoption.
Echocardiography is an essential diagnostic tool for evaluating cardiac disease, but reference values for echocardiographic variables may differ among dog breeds. Establishing breed-specific reference values is particularly important for Weimaraners because the breed is considered predisposed to dilated cardiomyopathy. The aim of this study was to establish breed-specific reference intervals for echocardiographic variables in clinically healthy Weimaraners. A total of 339 clinically healthy Weimaraners met the inclusion criteria. Each dog underwent cardiac auscultation, electrocardiography, and a standard echocardiographic examination. Measurements included cardiac chamber dimensions, ventricular wall thicknesses, indices of left ventricular size and systolic function, heart rate, and blood flow velocities across the aorta and pulmonary artery. Reference intervals were established for these variables. Significant sex-related differences were found in several measurements of left ventricular dimensions and wall thicknesses, left ventricular volumes, and left atrial and aortic dimensions. These reference intervals are important for the accurate echocardiographic evaluation of Weimaraners and may facilitate the early detection and accurate diagnosis of cardiac disease. To the authors’ knowledge, this is the first study to provide comprehensive breed-specific echocardiographic reference intervals for clinically healthy Weimaraners.
No takes yet. Share an insight, caveat, or question.
Filipejová et al. (2026) conducted a cross-sectional in Clinically healthy (reference intervals for echocardiography) (n=339). Male sex vs. Female sex was evaluated on Echocardiographic reference intervals (e.g., left ventricular dimensions, EDVI, ESVI) (p=<0.001). Significant sex-related differences were found in multiple cardiac dimensions and volume indices, emphasizing the need for breed- and sex-specific echocardiographic reference intervals in Weimaraners.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: