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The gradual increase in indications for radical prostatectomy over these last few years has focussed attention on the issue of surgical margin positivity. In terms of prognosis, a positive surgical margin is comparable to lymph node positivity. The routine adoption of the most advanced anatomo-histological methods has increased our 17.5% of positive surgical margins to 30.2% despite surgical indication having become increasingly more rigid. In addition, more precise preoperative staging by echo-guided biopsy of the seminal vesicles and of periprostatic spaces, has allowed patients with positive lymph nodes to be reduced to just over 1%.
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Graziotti et al. (1996) studied this question.
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