Key result
Nursing by hypertensive foster mothers induces sustained high blood pressure in normotensive rats.
Why the study?
The mechanism by which genetically normotensive rats develop sustained hypertension when nursed by spontaneously hypertensive foster mothers was unclear.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for maternal transmission of hypertension; does not support practice change pending human evidence.
Genetically normotensive Sprague-Dawley rats nursed by spontaneously hypertensive foster mothers develop sustained high blood pressure. Some factor related to the genetically programmed hypertension of the foster mother is probably transmitted to the infant rats through her milk. Alternatively, the hyperkinetic behavior of the mother may activate a hypertensinogen in young having the proper constellation of genes.
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McMurtry et al. (1981) studied Hypertension. Nursing by spontaneously hypertensive foster mothers was evaluated on Development of sustained high blood pressure. Genetically normotensive Sprague-Dawley rats developed sustained high blood pressure when nursed by spontaneously hypertensive foster mothers.
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