Key result
Percutaneous balloon mitral valvotomy improves aortic elastic properties acutely in severe mitral stenosis.
Why the study?
Aortic elastic properties in mitral stenosis have been little studied, and the effect of balloon mitral valvotomy on these properties is not well established.
Does percutaneous balloon mitral valvotomy improve aortic elastic properties in patients with severe rheumatic mitral stenosis?
Observational (n=32)
No
Does percutaneous balloon mitral valvotomy improve aortic elastic properties in patients with severe rheumatic mitral stenosis?
Successful percutaneous balloon mitral valvotomy acutely improves impaired aortic elastic properties in patients with severe rheumatic mitral stenosis.
Acute aortic elasticity gains after valvotomy merit prospective validation; leaves open effects on long-term outcomes.
Background: Aortic elastic properties in mitral stenosis have not been much studied. To date, only a few studies have studied the effect of percutaneous balloon mitral valvotomy (BMV) on aortic elastic properties. This was the first study done in Indian subcontinent in a tertiary care hospital in South India studying the effect of BMV on aortic stiffness in severe rheumatic mitral stenosis. We studied the relationship between aortic elastic properties and mitral stenosis and the effect of BMV on the same. Results: A total of thirty-two patients satisfying the criteria for severe mitral stenosis underwent balloon mitral valvotomy. All parameters were compared with age and sex-matched healthy volunteers. Aortic elastic properties were assessed by aortic strain and aortic stiffness index (ASI). The aortic strain was significantly higher in the patients with mitral stenosis 24–48 h after BMV, whereas the ASI was significantly lower. There was a significant decrease in mitral mean gradient and systolic pulmonary artery pressure after BMV. Mitral valve area significantly increased after BMV. Conclusions: Aortic elastic properties, as assessed by aortic stiffness, are usually impaired in patients with mitral stenosis, which improves following balloon mitral valvotomy.
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Rao et al. (2025) conducted an observational in Severe rheumatic mitral stenosis (n=32). Percutaneous balloon mitral valvotomy (BMV) vs. Pre-BMV baseline and age/sex-matched healthy volunteers was evaluated on Aortic elastic properties (aortic strain and aortic stiffness index). Percutaneous balloon mitral valvotomy significantly increased aortic strain and reduced the aortic stiffness index 24-48 hours post-procedure in 32 patients with severe mitral stenosis.
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